2C-P is a psychedelic phenethylamine and 2C compound first synthesized by Alexander Shulgin.
2,5-Dimethoxy-4-propylphenethylamine (commonly known as 2C-P) is a synthetic psychedelic of the phenethylamine chemical class that produces a long-lived, highly dose-sensitive array of psychedelic effects when administered. It is a member of the 2C-x family and was first synthesized and documented by Alexander Shulgin in his book PiHKAL (“Phenethylamines I Have Known and Loved”).
Along with other alkylated 2C-x substances like 2C-E, this compound is known particularly for its unusually long duration, powerful, sometimes overwhelming visuals, and intense “body load” (such as persisting nausea, muscle tension and general bodily discomfort). It is often described by users as a substance which is very similar to that of 2C-E yet distinct in its own effects.
Today, 2C-P is either used as a recreational substance or an entheogen, rarely sold on the streets and almost exclusively obtained as a grey area research chemical through online vendors.
This substance may be overly intense for those who are not already experienced with psychedelics due its often powerful effects and unusually long duration. For this reason, it is strongly recommended that one use harm reduction practices if choosing to use with this substance.
2C-P or 2,5-dimethoxy-4-propylphenethylamine is a substituted phenethylamine featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain. 2C-P contains methoxy functional groups CH3O- attached to carbons R2 and R5 and a propyl chain attached to carbon R4 of the phenyl ring. 2C-P belongs to the 2C family of phenethylamines which contain methoxy groups on the 2 and 5 positions of the benzene ring.
2C-P’s psychedelic effects are believed to come from its efficacy at the 5-HT2A receptor as a partial agonist. However, the role of these interactions and how it results in the psychedelic experience continues to remain elusive.